Paper by Dr. Caitlin Orsini and Dr. Luis Colon-Perez featured in eNeuro
From the eNeuro feature:
Assistant Professor Marcelo Febo and Professor Barry Setlow (both at the University of Florida) are pursuing this line of research further to determine the molecular changes that occur as a result of cocaine exposure. For example, correlating changes in functional connectivity detected by fMRI with DA receptor expression. Also, the fMRI observations could be related to behavioral modifications, such as decision making or impulsivity. Other directions could include other drugs of abuse or other imaging methods such as diffusion MRI to identify major tracts in the brain. And importantly, what are methods of restoration of functional connectivity following substance abuse, which could be examined using optogenetics or compounds that may reduce addictive behaviors.