Select Publications

Drug use disorders

Ravula A, Chandasana H, Setlow B, Febo M, Bruijnzeel AW, Derendorf H. Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol, and CB1 receptor antagonist in rat plasma: an application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant. Journal of Pharmaceutical and Biomedical Analysis, 2018, 160:119-125. [PMID: 30077950]

Jayant RD, Atluri V, Tiwari S, Kausik A, Yndart A, Colon-Perez LM, Febo M, Nair M. Multifunctional nanotherapeutics for the treatment of substance abuse induced neuro-HIV infection. Scientific Reports, 2018, 8(1):12991. [PMID: 30154522]

Orsini CA, Colon-Perez LM, Heshmati SC, Setlow B, Febo M. Functional connectivity of chronic cocaine use relative to a baseline reveals progressive neuroadaptations in neocortical, striatal and limbic networks. ENeuro, 2018, 5(4). [PMID:30073194]

Geste JR, Pompilus M, Febo M, Bruijnzeel AW. Self-administration of the synthetic cathinone MDPV enhances reward function via a nicotinic receptor dependent mechanism. Neuropharmacology, 2018, 137:286-296. [PMID: 29778945]

Colon-Perez LM, Pino JA, Saha K, Pompilus M, Kaplitz S, Choudhury N, Jagnarine DA, Geste JR, Levin BA, Wilks IJ, Setlow B, Bruijnzeel AW, Khoshbouei H, Torres GE, Febo M. Functional connectivity, behavioral, dopaminergic alterations 24 hours following acute exposure to synthetic bath salt drug methylenedioxypyrovalerone. Neuropharmacology, 2018, 137:178-193. [PMID: 29729891]

Thompson MF, Poirier GL, Davila-Garcia MI, Huang W, Tam K, Robidoux M, Dubuke ML, Shaffer SA, Colon-Perez L, Febo M, DiFranza J, King JA. Menthol enhances nicotine-induced locomotor sensitization and in vivo functional connectivity in adolescence. Journal of Psychopharmacology, 2017, 32(3):332-343. [PMID: 28747086]

Perez PD, Hall G, Zubcevic J, Febo M. Cocaine differentially affects synaptic activity in memory and midbrain areas of female and male rats: an in vivo MEMRI study. Brain Imaging and Behavior, 2017, doi:1007/s11682-017-9691-1. [PMID: 28236167]

Febo M, Blum K, Badgaiyan RD, Perez PD, Colon-Perez LM, Thanos PK, Ferris CF, Kulkarni P, Giordano J, Baron D, Gold MS. Enhanced functional connectivity and volume between cognitive and reward centers in naïve rodent brain produced by pro-dopaminergic agent KB220Z. PLoS One, 2017, 12(4): e0174774. [PMID: 28445527].


Aging, Alzheimer’s and other neurodegenerative diseases

Lin T, Liu G, Perez E, Rainer RD, Anton SD, Febo M, Cruz-Almeida Y, Ebner NC. Systemic inflammation mediates age-related cognitive deficits. Frontiers in Aging Neuroscience, 2018, 10:236. [PMID: 30127734]

Sahara N, Shimojo M, Ono M, Takuwa H, Febo M, Higuchi M, Suhara T. In vivo imaging for a diagnostic platform of tauopathy using rTg4510 mouse line. Frontiers in Neuroscience, 2017, 8:663. [PMID: 29375461]

DeSimone JC, Pappas SS, Febo M, Burciu RG, Shukla P, Colon-Perez LM, Dauer WT, Vaillancourt DE. Forebrain knock-out of TorsinA engenders impaired whole-brain functional connectivity and striatal free-water in a symptomatic mouse model of DYT1 dystonia. Neurobiology of Disease, 2017, 106:124-132. [PMID: 28673740].

Aydemir TB, Kim M-H, Kim J, Colon-Perez LM, Banan G, Mareci TH, Febo M, Cousins RJ. Zinc transporter ZIP14 (SLC39A14) is a gatekeeper against manganese-related neurotoxicity as occurs in Parkinson’s disease and dystonia. Journal of Neuroscience, 2017, 37(25): 5996-6006. [PMID: 28536273]

Bennion DM, Isenberg JD, Harmel AT, DeMars K, Dang AN, Jones CH, Pignataro ME, Graham JT, Steckelings UM, Alexander JC, Febo M, Krause EG, de Kloet AD, Candelario-Jalil E, Sumners C. Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats. PLoS One, 2017, 12(7):e0180738. [PMID: 28671997]

DeSimone JC, Febo M, Shukla P, Ofori E, Colon-Perez LM, Li Y, Vaillancourt DE. In vivo imaging reveals impaired connectivity across cortical and subcortical networks in a mouse model of DYT1 dystonia. Neurobiology of Disease, 2016, 95:35-45. [PMID: 27404940]

Febo M, Foster TC. Preclinical magnetic resonance imaging and spectroscopy studies of memory, aging, and cognitive decline. Frontiers in Aging Neuroscience, 2016, 8:158. [PMID: 27468264]

Thanos PK, Hamilton J, O’Rourke JR, Napoli A, Febo M, Volkow ND, Blum K, Gold MS. Dopamine D2 gene expression interacts with environmental enrichment to impact lifespan and behavior. Oncotarget, 2016, 7(15):19111-23. [PMID: 26992232]

Ofori E, Pasternal O, Planetta PJ, Burciu R, Snyder A, Febo M, Golde TE, Okun MS, Vaillancort DE. Increased free-water in the substantia nigra of Parkinson’s disease: a single-site and multi-site study. Neurobiology of Aging, 2015 Feb; 36(2): 1097-1104. [PMID: 25467638]

Sahara N, Perez PD, Ren Y, Lewis J, Febo M.  Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study. Neurobiology of Aging, 2014 Jun; 35(6):1364-1374. [PMID: 24411290]

Perez PD, Hall G, Kimura T, Ren Y, Lewis J, Febo M, Sahara N. In vivo functional brain mapping in a conditional mouse model of human tauopathy (tauP301L) reveals reduced neural activity in memory formation structures, Molecular Neurodegeneration, 2013; 8:9. [PMID: 23379588]